1,4- Phthalaldehyde

Tinye 6.0 g nke sodium sulfide, 2.7 g sọlfọ ntụ ntụ, 5 g sodium hydroxide na 60 ml mmiri n'ime 250 ml atọ flask olu na reflux condenser na mkpali ngwaọrụ, na welie okpomọkụ ka 80 ℃ n'okpuru edemede.Uzuzu sọlfọ na-acha odo odo na-agbaze, ihe ngwọta ahụ wee ghọọ uhie.Mgbe refluxing maka 1 h, a na-enweta ngwọta sodium polysulfide na-acha uhie uhie.

Tinye 13.7 g nke p-nitrotoluene, 80 ml nke ethanol mmepụta ihe, 0.279 g N, N-dimethylformamide na 2.0 g nke urea n'ime 250 ml olu atọ nke nwere oghere na-adapụ, reflux condenser na ngwaọrụ na-akpali akpali, kpoo ọkụ ma kpalie. igbari p-nitrotoluene iji nweta ihe ngwọta edo edo.Mgbe a na-eji nwayọọ nwayọọ bulie okpomọkụ ruo 80 ℃ ma nọgide na-adịgide adịgide, sodium polysulfide ngwọta nke a kwadebere na nzọụkwụ dị n'elu na-adaba, na ngwọta ahụ na-agbanye ngwa ngwa na-acha anụnụ anụnụ, wee gbanwee akwụkwọ ndụ akwụkwọ ndụ na-agba ọchịchịrị na agba aja aja, n'ikpeazụkwa na-atụgharị na-acha ọbara ọbara.A na-atụba ya n'ime awa 1.5-2.0, wee debe ya na 80 ℃ maka mmeghachi omume refluxing maka awa 2.A na-eme distillation uzuoku ngwa ngwa.N'otu oge nke distillation, a na-agbakwunye mmiri 100 ml, a na-anakọta 150 ml nke distillate, na uru pH bụ 7. A na-eme ka mmiri mmiri dị jụụ na ice ngwa ngwa iji mee ka kristal ìhè na-acha odo odo, nke a na-amịpụta na ether (30 ml × 5). ), kpochapuru ma kpoo ya iji nweta p-aminobenzaldehyde odo siri ike.

Tinye 5.89 paraformaldehyde, 13.2 g hydroxylamine hydrochloride na 85 ml mmiri n'ime 250 ml atọ olu olu, kpoo ọkụ na nwuo ka ha niile gbazee iji nweta ngwọta na-enweghị agba, wee tinye 25.5 g sodium acetate hydrate, debe okpomọkụ na 80 ℃ na reflux maka. 15 min iji nweta formaldehyde oxime (10%) ngwọta enweghị agba.

Na beaker 50 ml, tinye 3.5 g p-aminobenzaldehyde, 10 ml mmiri, dobe 5 ml concentrated hydrochloric acid, ma nọgide na-akpali.Ihe na-acha odo odo na-atụgharị oji ngwa ngwa ma na-agbaze na-aga n'ihu.Enwere ike ikpo ọkụ nke ọma (n'okpuru 6 ℃) iji gbazee ya niile.Mee ka ọ dị jụụ na mmiri ịsa mmiri nnu, na okpomọkụ na-agbada n'okpuru 5 ℃.N'oge a, p-aminobenzaldehyde hydrochloride precipitates dị ka ezigbo ahụ, na ngwọta na-aghọ mado.N'okpuru mkpali, 5-10 ℃ 5 ml nke sodium nitrite ngwọta na-adaba n'ime 20 min, na-akpali akpali maka ihe dị ka 20 min.A na-eji 40% sodium acetate ngwọta dozie akwụkwọ nyocha ọbara ọbara Congo ka ọ ghara ịnọpụ iche iji nweta ngwọta nnu diazonium.

Igbari 0.7 g nke crystalline ọla kọpa sulfate, 0.2 g nke sodium sulfite na 1.6 g nke sodium acetate hydrate n'ime 10% formaldehyde oxime ngwọta, na ngwọta na-atụgharị akwụkwọ ndụ akwụkwọ ndụ.Mgbe ịsachara, debe okpomọkụ dị ala maka 30 min iji nweta ngwọta isi awọ, gbakwunye 30 ml hydrochloric acid concentrated, bulie okpomọkụ ruo 100 ℃, refluxe maka 1 hour, ihe ngwọta na-egosi oroma, uzuoku distillation, nweta a na-acha ọcha ntakịrị odo siri ike, nzacha ma kpoo ka ị nweta ngwaahịa crumb nke p-benzaldehyde.A na-emegharị ngwaahịa ahụ na ihe mgbaze agwakọta nke 1: 1 mmanya na mmiri.